Toplash vs Babe Lash:Which Lash Serum Is Better?
Choose Toplash for independent clinical proof and a clean, prostaglandin-free formula. Toplash delivers +52.3% lash length and +31.9% volume in 8 weeks — verified by independent clinical testing, not brand-commissioned data. Babe Lash Essential Serum contains isopropyl cloprostenate (ICP), a prostaglandin analogue ruled "cannot be considered safe" for cosmetic use by the EU SCCS on February 2, 2026. And critically: at ~$17.50–$24.50/mL for 2 mL, Babe Lash is similarly or more expensive per mL than Toplash ($16.63/mL) — without the safety or clinical evidence to justify it.
At a Glance
Head-to-Head Comparison
A full factor-by-factor breakdown covering safety, formula quality, clinical evidence, and practical value.
| Factor | Toplash | Babe Lash Essential |
|---|---|---|
| Prostaglandin analogues | ✓ None | ✗ ICP present |
| EU SCCS (Feb 2026) compliant | ✓ Fully compliant | ✗ ICP not safe |
| Primary active mechanism | Triple peptide (MP-17, BTP-1, AT-3) | Prostaglandin analogue (ICP) |
| Clinical evidence type | ✓ Independent clinical trial | Brand data only |
| Lash length improvement | +52.3% at 8 weeks | Visible in 4–6 wks (brand claim) |
| Volume / fullness | +31.9% at 8 weeks | Not independently measured |
| Applicator type | Fine-tip precision brush | Fine-tip brush |
| Volume | 3 mL | 2 mL (smaller) |
| Price per mL | $16.63/mL | $17.50–$24.50/mL |
| Iris color change risk | ✓ None | ✗ ICP risk |
| Periorbital fat loss risk | ✓ None | ✗ ICP risk |
| Skin hyperpigmentation risk | ✓ None | ✗ ICP risk |
| Rebound shedding on stop | ✓ No rebound | ⚠ Possible PGA rebound |
| Safe for contact lens wearers | ✓ Yes | ⚠ ICP ocular risks |
| Safe for lash extension wearers | ✓ Yes | ⚠ Use with caution |
Ingredients Breakdown
Babe Lash Essential Serum and Toplash take fundamentally different approaches to lash growth — one relies on a prostaglandin analogue, the other on a precision triple-peptide system.
- MP-17 (Myristoyl Pentapeptide-17) — stimulates keratin gene expression; clinically shown to upregulate keratin up to 160%.
- BTP-1 (Biotinoyl Tripeptide-1) — strengthens follicle anchoring in the dermal papilla; +17% length and +19% thickness in 30-day testing.
- AT-3 (Acetyl Tetrapeptide-3) — extends the anagen (active growth) phase and reduces follicle miniaturisation.
- Panthenol (B5) — coats lash fibres, reducing brittleness and breakage along the shaft.
- Hyaluronic acid — sustains follicle zone hydration for an optimal growth environment.
- No prostaglandins, no hormones, no parabens — fully cosmetic, EU and FDA compliant.
- Isopropyl Cloprostenate (ICP) ⚠ EU SCCS: Not Safe — the primary growth active; a prostaglandin analogue ruled unsafe for cosmetic lash use (SCCS/1680/25, Feb 2026).
- Biotin (Pro-Vitamin B7) — supports keratin structure; limited topical absorption evidence for lash growth.
- Panthenol (B5) — moisturises and conditions lash fibres along the shaft.
- Amino acid complex (Alanine, Arginine, Glycine, etc.) — provides keratin building blocks; supportive but not primary growth drivers.
- Sodium Hyaluronate — hydration; also used in Toplash.
- Chamomile extract / Grape seed extract — soothing antioxidants; cosmetic-grade conditioning agents.
Babe Lash (rebranded as Babe Original) launched a prostaglandin-free Renewing Serum with peptides and botanical extracts. This newer formula avoids ICP — but it lacks independent clinical data for lash length measurement. Toplash remains the better-evidenced prostaglandin-free option with a verified triple-peptide mechanism.
Safety Profile: ICP in Babe Lash Essential Serum
The core safety concern with Babe Lash Essential Serum is the same as with GrandeLASH-MD and RapidLash: the presence of isopropyl cloprostenate, a prostaglandin analogue now flagged by EU regulators.
The EU Scientific Committee on Consumer Safety issued its final opinion on isopropyl cloprostenate (ICP) — present in Babe Lash Essential Serum — stating: "ICP cannot be considered safe for use in cosmetic products intended for application in the vicinity of the eye, at a concentration of 0.005%." This ruling applies regardless of product format or brand.
ICP stimulates melanin production in ocular tissue. Users with light eyes (blue, green, hazel) face the highest risk of permanent iris darkening.
Extended prostaglandin analogue use can cause orbital fat atrophy — a sunken, hollowed appearance around the eyes that may not fully reverse.
Darkening of eyelid skin along the application line is a documented ICP side effect — sometimes visible as a persistent discoloration after stopping use.
ICP prolongs the anagen phase artificially. On discontinuation, a period of accelerated shedding may occur as the natural lash cycle corrects itself.
Clinical Evidence: A Crucial Difference
How a brand measures and reports results matters as much as the headline number. Here's what Toplash and Babe Lash are each saying — and how credible each claim is.
Pricing & Value
Many shoppers assume Babe Lash is the cheaper option. When comparing per mL, the reality is different — and it changes the value calculation entirely.
Key insight: At typical retail prices, Babe Lash Essential Serum costs the same or more per mL than Toplash — yet comes in a smaller bottle, relies on a prostaglandin analogue now ruled unsafe by the EU, and offers only brand-reported (not independent) clinical evidence. Toplash provides measurably superior value when safety and evidence quality are included in the comparison.
Final Verdict
Better Safety. Better Proof. Same or Lower Cost Per mL.
Babe Lash Essential Serum contains isopropyl cloprostenate — the prostaglandin analogue that the EU SCCS ruled "cannot be considered safe" for cosmetic use in February 2026. It also costs the same or more per mL than Toplash, in a smaller bottle, with only brand-reported evidence. Toplash wins on every measurable dimension: independently verified +52.3% lash length, zero prostaglandin risk, EU SCCS compliance, and competitive pricing at $16.63/mL for a 3 mL bottle.
Try Toplash — $49.90 for 3 mL
Toplash Lash & Brow Serum
MP-17 + BTP-1 + AT-3 with independent clinical data: +52.3% length and +31.9% volume at 8 weeks. Prostaglandin-free, paraben-free, ophthalmic-tested and extension-safe.
Shop Toplash SerumFrequently Asked Questions
Does Babe Lash contain prostaglandins?
Yes — Babe Lash Essential Serum contains isopropyl cloprostenate (ICP), a synthetic prostaglandin analogue listed in its ingredient deck. The EU SCCS ruled in February 2026 that ICP "cannot be considered safe" for cosmetic application near the eye area. Babe Lash's newer Renewing Serum is prostaglandin-free, but the original Essential Serum still contains ICP. Toplash contains no prostaglandins in any formulation.
Is Babe Lash Essential Serum safe?
Babe Lash Essential Serum contains isopropyl cloprostenate (ICP). The EU SCCS issued a final opinion on February 2, 2026 ruling ICP "cannot be considered safe" for cosmetic use near the eyes at any concentration up to 0.005%. Known risks include iris color change (especially in light-colored eyes), periorbital fat loss, skin hyperpigmentation along the lid line, and rebound shedding when discontinued. The Renewing Serum is the safer Babe Lash option — though Toplash offers stronger independent clinical evidence.
Which shows faster results — Toplash or Babe Lash?
Babe Lash Essential Serum's ICP may produce early visible changes through prostaglandin-mediated lash extension, with brand-reported visibility in 4–6 weeks. Toplash shows 98% of users noticing visible improvement by day 21, and independently verified +52.3% length increase at 8 weeks. The key distinction is evidence quality: Babe Lash's timeline is brand-reported perception; Toplash's numbers are independently measured clinical data.
What is the difference between Babe Lash Essential Serum and Babe Lash Renewing Serum?
Babe Lash Essential Serum contains isopropyl cloprostenate (ICP) — a prostaglandin analogue now ruled unsafe by the EU SCCS. The Renewing Serum is a newer prostaglandin-free formulation using peptides and botanicals. If choosing between Babe Lash products, the Renewing Serum is the safer option. However, Toplash's triple-peptide formula (MP-17, BTP-1, AT-3) has independent clinical backing that neither Babe Lash product currently matches.
Which is better value — Toplash or Babe Lash?
Toplash offers better value. At $49.90 for 3 mL ($16.63/mL), it is the same price or cheaper per mL than Babe Lash Essential Serum at $35–$49 for 2 mL ($17.50–$24.50/mL). Toplash provides a larger bottle, independent clinical verification, EU SCCS compliance, and no prostaglandin risk — making it the superior investment at a comparable or lower per-mL cost.
Can I switch from Babe Lash to Toplash?
Yes. Switch directly from Babe Lash to Toplash without a wash-out period. When stopping a prostaglandin analogue, a brief lash adjustment phase is normal as the cycle resets from its artificially extended state. Applying Toplash daily through this transition supports follicle health with its peptide complex. Allow 12 weeks for full Toplash results to establish from the transition point.
Is Babe Lash or Toplash better for lash extensions?
Toplash is significantly better for use with lash extensions. Its lightweight water-based formula strengthens the natural lash without disturbing extension adhesive bonds. Babe Lash Essential Serum's ICP content carries additional ocular risk near extension application zones, and the prostaglandin mechanism can alter the natural lash cycle in ways that affect extension retention and natural lash health over time. Many lash technicians recommend only peptide-based serums for extension wearers.
Published: Jun 20, 2026
